Wednesday, April 15, 2020
20 Opinion Essay Topics How to Write about the History of Architecture in an Interesting Way
20 Opinion Essay Topics How to Write about the History of Architecture in an Interesting Way It is a known fact that the content of an essay is determined by the subject matter to be discussed but its structure relies heavily on the topic you choose. Therefore, when writing an opinion essay, the first step to shaping your opinion and that of the reader starts with selecting a topic that wakes up the urge to learn in the reader. Writing on the history of architecture is a task that can be simplified if a topic that truly interests the reader is chosen. This article will attempt to provide you with some topics on the history of architecture which will serve as a portal into learning more about ancient cultures and their influences on the architecture of their time. Dissecting the Role of Ancient Cultures in Driving Architectural Growth Architecture in the Neolithic Era and the Birth of Modern Architectural Designs Neolithic Architecture and its Role in Human Creative Growth Spotting Religious Influences in Ancient Architectural Design Understanding the Importance of Religion in Ancient Architecture and Creative Design The Effects of Roman Architectural Innovations to Urban Planning Outlining the Architectural Innovative Feats of the Roman Era Discussing Islamic Architecture and the Cultures that Influenced it The Unchanging Face of Chinese Architecture through the Years Chinese Architecture and its far-reaching Influence Over Asia The Incan Architecture and the History of Suspension Bridges European Medieval Architecture and its Religious Influences The Need for Defense and Offense in Ancient Societies and Medieval Architecture Gothic Architecture and the Rise of the Christian Religion in Europe The Rise of Renaissance Architecture and the Structures it Inspired The Spread of Italian Renaissance Architecture and its Impact in 16th Century Europe The Impact of Aksumite Architecture across The Sahel Region The Spread of Gothic Architecture and the Role of French Architects A Study of African Architecture and its External Influences The Incan Architectural Feats and its Impact on Asian South American structures Above are the topics on the history of architecture which you can use to develop your opinion essay on ancient cultures and the architectural revolutions they birthed. You can choose any of the listed topics as yours or seek some inspiration from them. Also, we intend to provide a sample essay using a topic listed above as the inspiration behind it. So please stay tuned to learn more about writing aà greatà essay. Lastly, facts from the complimentary article which provides 10 facts for an opinion essay on the history of architecture will be used in developing the sample essay in the coming paragraphs. Sample Essay: Dissecting the role of Ancient Architecture Cultures in Driving Architectural Growth The history or architecture through the ages has been replete with the cultural beliefs of the people who created the structures that defined bygone eras. In my essay, I intend to explore the role of culture as a determining factor in advancing the field of architecture as we know it. To effectively discuss culture and ancient architectural growth, I believe it is important to first understand the meaning of culture and what makes up the cultural fabric of a society. Culture is defined as the ideas, customs, religious beliefs and social behavioral patterns of a society. As man evolved from being a solitary creature to living in communities, cultural values slowly became established and were represented by art works on cave walls. With time, circa 10,000 BC, the Stone Age witnessed the first time man created architectural structures to serve as housing for the family unit. As with the art forms that defined the Stone Age, 10,000 BC architecture was also inspired by the culture of its people. Therefore, architecture in the Neolithic era consisted of stone works arranged in circular form to accommodate both prehistoric man and the domesticated animals they kept for feeding. Here, the farming and gathering culture prevalent in the Neolithic age led to partitioning the home into rooms and sections for the keeping of both plant and animal life. The need for constant trips to water grounds and to gather food also played a role in advancing the creation of road paths for easy movement. The cultural influence on architecture also continued after the prehistoric era as can be seen in the architectural forms known as Mesopotamia architecture. In ancient Egypt, the belief in multiple gods and their direct influence on every sphere of human life led to the need to create elaborate homes for these gods on earth. Therefore religion played a huge role in architectural innovation as large monuments such as the Sphinx statues- tributes to the god Ra- were ingeniously built with the use of stone, mortar as well as advanced pulley systems which were marvels at that time. European architecture is not also bereft of cultural influences. In ancient Rome, large temples were also built to accommodate the many gods that influenced the roman society. But the architects in ancient Rome took innovation a step further by building civic structures such as the amphitheatre, triumphant arch, baths and gladiatorial grounds to cater for the entertainment, learning and relaxation needs of humans. While in medieval Europe, a culture of warring, annexation and external aggression led to the building of architectural marvels dedicated to the art of defending and attacking the enemy. With the advent of Christianity and the Christian way of life, the architectural landscape of Europe changed to accommodate the building of large cathedrals using ancient roman patterns as well as the Italian renaissance techniques which integrated perspective in architectural pieces to inspire the people. Islamic architecture also took inspiration from the architecture of ancient Iran as can be seen from the recurrent use of large domes and spires in the building of mosques. Finally, African architecture in the colonial era is a great indication of the effects of culture in architecture. This is because it integrated African, European, Christian, Arabic and Islamic cultures in the architectural masterpieces that can be seen across the continent. References: Fletcher, B. (1961). A History of architecture on the Comparative Method. 1st ed. New York: Scribner. Harland, J. and Bell, W. (2003). The Architecture of Ancient Greece: An Account of Its Historic Development. The Classical Weekly, 46(16), p.242. Sales Carbonell, J. (2014). Roman Spectacles Buildings as a Setting forà Martyrdom and its Consequences in Christian Architecture . Journal of Ancient Architecture and Archaeology. Buiskikh, A. (2007). On the Question of the Stylistic Influences reflected in the Architecture and Art of Chersonesos: Snake-legged Goddess or Rankenfrau. Ancient Civilizations from Scythia to Siberia, 13(3), pp.157-181. Shilliam, R. (2015). Colonial Architecture or Relatable Hinterlands? Locke, Nandy, Fanon, and the Bandung Spirit. Constellations, 23(3), pp.425-435. Williams, K. (2014). Architecture, Astronomy and Sacred Landscape in Ancient Egypt by Giulio Magli. Nexus Network Journal, 16(3), pp.825-828. Amirkhani, A., Okhovat, H. and Zamani, E. (2010). Ancient Pigeon Houses: Remarkable Example of the Asian culture crystallized in the architecture of Iran and central Anatolia. Asian Culture and History, 2(2).
Thursday, March 12, 2020
Extended Project Dissertation Regenerative Medicine Essays
Extended Project Dissertation Regenerative Medicine Essays Extended Project Dissertation Regenerative Medicine Essay Extended Project Dissertation Regenerative Medicine Essay Essay Topic: Extended With the continued research going on into this new, potential way of curing many diseases that 20 years go we would never have thought could have been cured, can it do the same for the neurological condition, multiple sclerosis? And how effective is it in doing so? Many reports have come out of stem cells being effective in mice to cure the disease but with the many controversial points that come with the use of stem cells would alternative, existing methods be a better way of treating it? Are the instrumentation drugs of today more effective in treating the condition and are they a more realistic thing to be using? Also is it actually a good thing if we are finding new cures to all of these diseases? With he worlds population rapidly rising and resources running out to feed everybody and supply them all with energy, would it be better if we continued as we are and stopped playing God? These are the issues that will be discussing in this essay. Introduction and Research What is multiple sclerosis? An abnormal condition of a part, organ, or system of an organism resulting FRR mom various causes, such as infection, inflammation,environmental factors, or genetic defect, and characterized by an identifiable group of signs, symptoms, or both. Is the definition of a disease in an online free dictionary[l] and they effect peoples lives in in many ways, nearly all of them being bad and detrimental to both society, families and the world. They can be passed on by direct transf er of bacteria, viruses and other germs. However they can be passed on by sex, either in the form of sexually transmitted diseases or by genetically passing down to offspring during fertilization. A disease that is linked to being both hereditary and environmental is the unrepresentative disease, Multiple Sclerosis. Multiple Sclerosis is a disease that affects the nervous system of the body, specifically in the brain and spinal cord Every river cell in the body is surrounded by a protective layer known as the myelin sheath which enables electrical impulses that travel around the body to reach their destination hundreds of times quicker than it would without one. If a person has Multiple Scleroses, MS, then this myelin is broken down partly and therefore messages are not sent to the brain or spinal cord as efficiently. This results in a sufferer or MS to experience potential symptoms such as: loss of vision, in one eye usually, uncontrollable muscle spasms and muscle stiffness, difficulties in balance and co-ordination and people find they often suffer room tiredness and fatigue. There are two main types of Multiple sclerosis that sufferers get. The first, relapsing remitting MS, occurs in approximately eight out of ten people that are diagnosed with MS are diagnosed with this form. Somebody with relapsing remitting multiple sclerosis will have periods without suffering any of the symptoms usually associated with the disease, then they will suffer periods where the symptoms are severe and the patient may become partially blind or be unable to move. However, this period will pass and the sufferer will go back to almost normal again without showing any signs or having the disease. This period may last weeks, months or even years and this is why diagnosing this type of MS is so hard to do because of how irregular it is it can be mistaken for a number of temporary conditions and people dont report when they experience symptoms because they have had them before and was k. After 15 years of so, about half of people that have got relapsing remitting MS will go on to develop secondary progressive multiple sclerosis. This is much like the first form and people may still experience relapses but the symptoms will worsen over time and they may not fully recover from their relapse. Primary progressive MS is the least common type of sclerosis. This is where there are no periods of remission and symptoms just worsen over time with no break periods. Treatments for multiple sclerosis: Currently there is no cure for Multiple sclerosis but there are a number of treatments that can help Relapsing remitting multiple sclerosis can be treated with drugs called disease modifying drugs, these are not a cure for the disease but instead can reduce the severity of the symptoms in a sufferer and can reduce the number of relapses they have. However they are not suitable for all sufferers of Multiple Sclerosis. There are currently 10 licensed Dams (disease modifying drugs) [3] these are: Bugaboo (trinitrotoluene) oral tablet taken once a day. Available if patient has had at least two relapses in the past two years. Avenue (interferon beta-I a) -? Injection available if patient has had two relapses in the past two years. Beefeater (interferon beta-I b) available if patient has had two relapses in the past years, it is injected. Capstone (glitterati acetate) -? another injection available after two relapses in the same period of time. Octavia (beta interferon-I b) injection if patient has has 2 relapses in 2 years. Galilean (fondling) -? available if patient is still experiences despite treatment with one of the beta interferon. It is an oral tablet taken once a day. Elementary (lumberman) available for treating the active relapsing remitting form of multiple sclerosis. It is given to patient via a drip once a year. Pleurisy (vociferation beta la) injection for people living in Scotland for sufferers that have had 2 relapses in 2 years. Rebuff (beta interferon- 1 a) another injection available for patients suffering 2 relapses in the past 2 years. Deciders (timidity fumigate) used to treat active elapsing remitting MS. Approved by the NASH and became available in autumn 2014. It is a oral tablet that should be taken twice a day. Disability (nutritional) available if you have had 2 relapses in one year or if severity of relapses has increased once another DIM has been taken, given by drip monthly. There are also a wide range of other treatments available to treat multiple sclerosis. Physiotherapy can be used to make day to day living with MS more bearable and steroids can be given to patients to speed up recovery times from relapses. Causes of Multiple Sclerosis: Multiple sclerosis is an autoimmune condition. This means that the bodys defense against harmful diseases (the immune system) is affected in some way and that causes the immune system to change from attacking foreign viruses to attacking healthy body tissue- in multiple sclerosis this is the healthy Myelin that surrounds nerve cells in the body. The myelin is broken down by the bodys own immune system, nervous impulses are less efficient in traveling to the bodys Central Nervous System. As a result of this, in the places where the myelin on the myelin sheath has been thinned or destroyed, a hard region or scar is left in its place, often referred to as a sclerosis. Where there is multiple Of these hardened scars on different places On the brain or spinal cord is where the autoimmune disease gets its name from- Multiple Sclerosis. The causes of Multiple sclerosis are currently unknown; however scientists believe the main causes of the disease are a combination of genetic and environmental factors and are putting the pieces of this complicated puzzle together [4]. Genetic factors- genes are pieces of genetic information that code for the production of proteins, molecules that are essential for many of the bodies vital functions. Occasionally come genes may be faulty ND produce defective proteins. This is the cause of many of the diseases we see today however this isnt what is believed to occur in multiple sclerosis. It is thought that individuals that are affected by MS have slight variations, called polymorphism, which are healthy genes that fit badly when combined together in DNA and thus cause healthy cells around it to be altered, especially cells involved in the bodys immune system. This bad combination of genes is then passed down through the generations by normal mechanism of inheritance and therefore there is a strong link of multiple sclerosis being hared within families. There are a few genes that have been identified to make people more likely to get MS, in particular the HAL (also known as major historiographys complex, as containing the most MS susceptible gene. These proteins are found on the surface of all body cells. They act as a messenger to the immune system telling the body whether a cell is foreign or part of the body and whether it should be attacked or not. These proteins are usually healthy and therefore there must be another reason for them being altered to become defective. Scientists believe this is down to environmental actors. One theory is that a virus that is usually lying dormant in the body may disturb the immune system and therefore cause the disease to develop. There is probably on one MS virus but actually a combination of a common virus such as measles that acts as a trigger for MS. This trigger activates white blood cells (lymphocytes) in the bloodstream, which enter the brain by making the brains defense mechanisms (I. . The blood/brain barrier) vulnerable. Once inside the brain, these cells activate other elements of the immune system in such a way that they attack and destroy myelin. It is also Hough that vitamin D, the vitamin we get from sunlight, is linked to the disease. There has been a correlation between people that receive low levels of vitamin D have a higher chance of developing MS. A number of studies have i ndicated that smoking is also linked to the development of Multiple Sclerosis. It is not clear why this happens however it has been theorized that chemicals in cigarettes may have some sort of effect on the immune system and may alter it. Smoking effect on the progression of multiple sclerosis is also being investigated as it could be the fact that smoking leads to the regression of the disease being quicker and it may cause relapses to be more often and more severe. It is estimated that around 100,000 people in the UK are suffering with Multiple sclerosis at this present time, with 2. Million Cases Of MS in the world. Every week in the United States there are 200 people diagnosed with MS so this is a disease that has worldwide influence and is a major problem worldwide however it is incurable, this needs to change. Although the disease is not fatal in itself, some complications that can arise from severe MS, such as pneumonia, can be. This means that in order to reduce the numbers of people and families offering with this terrible disease we as a race need to find a new way of treating it. This might be achieved through regenerative medicine. Regenerative medicine: Regenerative medicine is the process by which scientists are able to restore normal bodily functions by repairing or replacing damaged or malfunctioning cells and tissues in cells[5] and although it is in its early stages of development, it is bringing huge advances in the field of medicine as it could provide the cure for many different diseases such as Multiple sclerosis, dementia, strokes, heart disease and many types of cancer. For example, the guardian reported a recent trial on 18 people suffering with two different types of muscular degeneration, the leading causes of blindness in adults and children in the world, Stardusts muscular dystrophy and dry atrophic age- related muscular degeneration[6]. The patients had embryonic stem cell therapy on their eyes and were cured of sight loss without any side effects. Whatever sources of potential bias the guardian may have, being a politically left leaning newspaper, the point still remains, stem cell therapy and regenerative medicine has and will continue to provide a big source of hope n the fight against many different deadly diseases. Regenerative medicine mainly comes in the form Of stem cell treatment, allowing scientists to use undifferentiated cells and turn them into any cell in the body to serve any function. This is a huge breakthrough in science and medicine as it enables anything to be made, it solves the problem of organ storage or a lack of organ donors, as hearts and lungs can just be grown in a lab and transplanted into the patient that requires them. Stem cell Research: In the early 1 sass, European researchers discovered that various types of load cells all came from a particular stem cells, however it was not until 1 963 that the particular type of self-renewing cells was first described in mice bone marrow cells by Canadian researchers Ernest A McCullough and James E Till [7]. Since that time there has been continued efforts to grow and differentiate adult animal and human stem cells in a lab. This was made a lot easier in the 1 sass and sass where there was an introduction of techniques for targeting and altering genetic material and methods for growing human cells in the laboratory. These advances really opened the doors for human tem cell research. The breakthrough came in 1998 when James Thompson, from the university of Wisconsin in Madison, successfully removed embryonic cells from a fertility clinic and cultivated them in a lab, this launched stem cell research into the limelight. Since then there has been plenty of further research that suggests that these embryonic stem cells can specialist into any cell in the human body which, if mastered, could open up a whole new world of new medicine that could change millions of peoples lives. As stem cells were only brought into the public attention in 1 998, the technology is still elatedly new and still in its youth. There have been no clinical trials of stem cell treatments as of yet however; adult stem cells are already being used in treatments for over one hundred conditions including leukemia, Hunters syndrome and heart disease. So stem cells are the answer to all of humanities works yes? Unfortunately that is not that case as this new technology does not come with many controversial parts with many people opposing to this potentially lifesaving new technology, the main point of controversy is the use Of embryonic stem cells and the ethical considerations behind that. In this document I will be discussing the main treatments of multiple sclerosis and relating it back to the question of is Regenerative Medicine the most effective way of treating Multiple Sclerosis? O I will evaluating whether other methods of treating multiple sclerosis is more effective than stem cell research then I will be coming to a conclusion at the end of the essay. Discussion Effectiveness of Stem Cell Treatment: The first issue to talk about is whether stem cells are an effective method of treating any disease and then to focus down on the specific disease we are looking at. There is no doubt that the discovery of these undifferentia ted, unspecified cells is a hugely promising unearthing, however are they a truly effective way of treatment? Do they actually do all the things that scientists promise they can do? And are they sustainable? Firstly, lets look at the plus sides of stem cells, what they can do that is beneficial to the body and what they can do to aid the recovery of a disease or illness. Diseases such as cancer or conditions such as birth defects are thought to occur because of problems in the differentiation process, an understanding of the development that appends in normal cells and stem cells will help scientists treat the developmental errors that can occur. This will help in two fields because we will know more about the development of cancers and birth defects as well as discovering more about how stem cells differentiate (to make or become different in the process of growth or development), and this will help us be able to use stem cells more effectively in turn at treating these problems, working in a positive feedback model. The next advantage of stem cells, according to website explore stem cells is that there is another potential application of cell based therapies [8]. This is when stem cells are used to grow specific cells and then are bound together using a mould to create a completely new organ or tissue. This is a huge advantage to stem cells as currently when a patient needs to new organ they get one transplanted from an organ donor. At this current time there is nowhere near the required amount of organ donors to supply the needs of people needing an organ transplant and with this new regenerative technique instead of waiting for a new organ to be donated, a new organ can be grown from scratch to fit into your body. This will dramatically reduce the amount of people dying whilst being on the waiting lists for an organ transplant. Stem cells can benefit those suffering from Parkinson disease, type 1 diabetes, arthritis, burn victims and people with cardiovascular diseases (the biggest killing disease in the UK- BBC) using this method of treatment. Stem cells also have the potential to reverse the effects of diseases. Stem cells are directed into differentiating into specific cell types, they can be fed into the body, providing a renewable resource of replacement cells for the patient. For example, people with heart ease can have stem cells differentiated into heart muscle cells to replace cells damaged by the disease, in Parkinson disease damaged brain cells can be reversed by replacing them with new healthy brain cells, reversing the effect of the disease. An even more exciting prospect is to address genetic defects that are present from birth by restoring function and health with the introduction of normal healthy cells that do not have these defects. Burn victims will, instead of suffering large amounts of pain from their injuries and instead of having to wait for donor tissues, they can have new healthy skin ells implanted onto the patient. Scientists are hoping to do this by growing skin cells in a lab from a very small piece of skin by triggering stem cells to differentiate outside the body so that large burn areas can be covered by a relatively small amount of initial skin cells. The final major benefit to stem cells research is that is provides a huge role in the pharmaceutical industry and is involved heavily in drug development. Any new drugs that are being tested for human consumption can be tested on human stem cells before they are released for their safety. This could be the case with a new anti- amour drug for example, and if the conditions that the drugs are tested in are in the correct conditions then the results could end up being very accurate and the drugs could be shown to be safe for human use and will help to treat people with life threatening diseases. The advantages of stem cells are well documented and for people with serious conditions could be a source Of major hope that one day they could be the cure for them. O it would seem as though stem cells are completely fine, effective and the answer to all of our prayers. This is not the case however, stem cell therapy is till a very controversial topic, and this is nearly all down the disadvantages that come about with stem cells. Firstly it is where stem cells are collected from. Many stem cells are collected from embryos to form embryonic stem cells; these are a very good type of stem cell to use as embryos are full of unspecified cells as eventually these will turn into a new baby human being. However, if embryonic stem cells are used then effectively there is no chance that the embryo will develop into a new-born and an abortion will take place. For many people this raises the argument of at what point does an embryo come a human and therefore has the same rights as every other person? If that point comes about at fertilization or during the embryonic stage then what occurs to extract stem cells out of these early life forms is effectively murder and therefore should not happen. Embryos are not the only place stem cells can be extracted from however, umbilical cords that are disposed of and bone marrow can be a plentiful source also however according to one source found[9], religious groups Religious groups claim that because embryonic stem cell research requires the subsequent destruction of the embryos used, it is a form of abortion. They sustain that creating embryos for the sole purpose of commercial use, followed by their disposal is morally unacceptable, and strongly oppose the area of study while adult and cord stem cells are readily available instead. Perhaps the biggest risk with this new area of research is the unknown. The introduction of stem cells into the body is permanent and this means there may be some long term side effects that we do not know about at the moment that might become clearer later along in the process. These are bad because we would not be able to reverse the effects of these side effects, A French study ten years ago found that spiniest of genetically altered bone marrow transplants developed leukemia years after their allegedly successful transplants had cured their severe combined immunodeficiency. Some research on rats in California found a way of successfully curing paralysis, however some small cysts appeared in the area near where the stem cells were injected. However harmless these were to rats, the effect of this to humans is still questionable. Other side effects that could be because of stem cell research include growth of strange objects such as teeth bones and hair on unusual areas, if this was done using embryonic stem cells these continue to grow wrought the patients life. Around 20% of rats injected with embryonic stem cells later die of some kind of cancerous tumor. This could be completely by chance but this high statistic is enough for large groups of people to doubt whether regenerative medicine is the right way to go in medicine. Another major cause for concern in stem cells is that in some cases it is known for differentiated stem cells to be rejected by the host body. A report published in nature in 2011 showed that when a specific type Of stem cell, induced plenteous stem cells (epics), used to treat diseases, found hat epics could face rejection by the immune system, even when injected into the same person who donated the cells. This immune response could destroy the transplants, rendering them ineffective as treatments. Although a different report published in 201 3 by Nature seemed to show that these epics were effective in being transferred in genetically identical mice and not triggering a strong immune response. This contrasting information shows just how unpredictable stem cell research is and that it may not be the best way to treat diseases. In conclusion then think that on balance using generative methods in treating diseases in general are a very effective way Of doing things however it is not a completely safe and iris free process as in my opinion still think that for it to be the best method stem cell therapy can be it still needs more research on the long term effects of the process, but from early indications it is looking promising barring a few studies. However what about in our specific disease? How does a using stem cell therapy affect the multiple sclerosis disease? Is it as effective at treating it as the other conditions already mentioned? At present there are no treatments that pacifically target the abnormal immune responses in MS. Current approaches, such as interferon, capstone, or immune suppressants all act in a non-specific manner blocking immune responses against the myelin sheath. While these approaches are useful for reducing the severity of disease, they do not repair the damage to nervous system tissue that has already occurred and therefore they cannot cure multiple sclerosis. However stem cells provide a different way Of treating the disease. Instead Of protecting the myelin sheath they allow it to be destroyed however it is replaced by stem cells that re externally differentiated in a lab before injected into the spinal cord or in the blood stream ready to be transferred to the brain. It is either this repair method used or, according to the MS society website, the nerve cell can be prevented from being damaged. This is called imperfection and is an active area of research involving adult stem cells from the bone marrow called mechanical stem cells. These stem cells are taken from human umbilical cords [1 1] that are donated after normal healthy births so this avoids the debate over the controversial topic of where the stem cells are oaken from. These stem cells are then screened for infectious diseases, with only about 1 in 10 umbilical cords passing screening tests. The advantages of this treatment are that anybody can be treated using these stem cells as they do not need to be matched with their genome, the stem cells are easily extracted and there is a large supply of them, and these HI-?CIT mechanical stem cells are a lot more robust then other types leading to a higher success rate. So that type of stem cell treatment by the stem cell institute seems relatively effective in terms of protecting the myelin sheath from the autoimmune response brought about by MS. However this is not the only study I found that seems to show that Multiple sclerosis can be cured by regenerative medicine. Scientists at The Scripps Research Institute (TSR) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, the compounds boost a population of progenitor cells that can in turn repair MS-damaged nerve fibers. [1 2]. In this report, it is shown that a previous drug penetration, that was used to treat Parkinson disease, as been shown to increase numbers of electioneered (cells that make the myelin sheath and wrap it around the nerve fiber) in the nerve sharply, and thus increasing the amount of myelin produced. To do this scientists screen over 1 0,000 diverse compounds to see if any could potentially cause OPS cells to differentiate, and the already tested drug penetration seemed to do that already. However, not all studies show this trend however, a journal on PLOPS one[1 3] shows that a new type of stem cell, neural stem cells (NCSC), does not have a major influence on the clinical course of room-induced EYE. Improving the efficiency at which NCSC home to inflammatory sites may enhance their therapeutic potential in this model of CONS autoimmunity Meaning that the new type of stem cell does not have any effect on the number of electioneered cells being produced to repair the myelin sheath, and thus showing that regenerative medicine isnt always effective.
Tuesday, February 25, 2020
Solar Energy Systems Research Paper Example | Topics and Well Written Essays - 3500 words
Solar Energy Systems - Research Paper Example The available fossil fuel stocks are believed to be sufficient enough for thirty or forty years more if the consumptions continues in the present rate. Even though explorations are going on for finding out new fossil fuels sources, the outcomes are not much encouraging. In short, it is necessary for the mankind to identify alternate energy sources which are capable of replacing fossil fuels. Even though plenty of energy sources are in discussion for future use, all of them have some kind of drawbacks. The recent tsunami attack on Japanââ¬â¢s nuclear power stations and the subsequent problems raised many questions about the logic of relying heavily on nuclear power in future. Solar energy, wind energy, tidal energy, geothermal energy, hydroelectric power etc are some of the other energy sources which are discussed at present as future energy source. However, solar energy seems to be alternate option in future when we consider its renewable nature. Chapo (2004) mentioned that ââ¬Å"On a smaller scale, there are solar panel packs that fold out like a small ledger and are used to power up anything from laptops to cell phonesâ⬠(Chapo). One of the most difficult problems associated with the utilization of solar energy is the problems in converting solar energy into other forms of useful energy. The current solar energy conversion technologies are extremely poor and therefore we can use it only for purposes like boiling water and in solar devices such as calculators, watches etc. In other words, the available technologies to convert solar energy into useful forms of energy are expensive now. This paper analyses different topics related to Solar Energy Systems. A solar collector consists of a network of pipes through which water (or in colder climates, antifreeze) is heated. Collectors come in various sizes, with 4 by 8 feet (1.2 x 2.4 m) the most common. The three most common mounting systems for solar
Sunday, February 9, 2020
Airline industry applications Essay Example | Topics and Well Written Essays - 4000 words
Airline industry applications - Essay Example With the help of using different mobile applications such as QLOUD and Knowledge-driven In-flight Solution (KIS), it is easy to access distinct sorts of information anytime and in anywhere (Ravichandran, 2011). In earlier times, the mobile applications were used in a modest way; however, these have been progressed in this modern day context providing advanced facilities to the people. Mobile applications can be defined as software or programs that are used in mobile devices (Islam, Islam & Mazumder, 2015). The airline industry generally uses the above stated mobile technologies or mobile applications amongst others to enhance the service processes and also offering best services to the passengers. In this modern day context, the global airline industry is identified to use mobile applications for deriving cost-effective solutions in their respective operational functions. It can be apparently observed that the worldwide airline industry has changed with significant improvements made in the respective business processes by using mobile technology. These improvements could be reckoned as developing the facility of electronic ticket and introducing the system of online check-in. By using mobile applications, it can be inferred that the airline industry is able to ensure providing better and quality services to the customers with having greater control over costs to be incurred during the process (NIIT, 2012). There are several airline based companies that have become much popular for providing quality services to the users by the use of distinct mobile applications. In this regard, such airline companies include Qatar Airways, Emirates Airways, British Airways and United Airlines. These four popular airline companies use different mobile applications including QLOUD, KIS, electronic or wireless bag tag and Travel card and Travel wallet. These mobile apps have been taken into concern for discussion while comparing the same amid
Thursday, January 30, 2020
Ha Long Essay Example for Free
Ha Long Essay A customer buys products based on their look and the quality inside . This is an example of how tourists choose their tourist destination and I have a wonderful destination that everyone should come once time in their life Ha Long . Ha Long is one of seven nature wonders of the world. Visiting Ha Long bay, you can experience the diversity of natural views, from sandy beaches to thousand year old rocky mountains. Why should you choose Ha Long bay to visit ? The word Ha Long in Vietnamese means the dragon descends into the sea and he legend says that the island of Ha Long was created by a great dragon who lived in the mountain, it sounds very interesting. First, I will let you know about the wonderful scenery. When you come to Ha Long, you can just describe as a wow , from great father mountain to thousand year old caves, from sandy beach to diving to discover the sea . Ha Long bay will lead you from one surprise to another. Beside that, Ha Long has had a particularly significant position because of its location oââ¬â¹n the important communication and trade route between China, Japan and Thailand , so you can see the great combination of culture of four countries. What will you do when you come to Ha Long bay ? As I said, Ha Long is a great combination of scenary and culture , so there are so many trips that take you to experience the beauty and culture of Ha Long . You will visit Ha Long on a cruise , which is called cruise tour that will lead you visit all places in Ha Long , it looks like you are mixing with the natural , beauty of sea , mountains and caves .Come to Ha Long bay, you will have agreat opportunity to get experience about life on water , which means people live all their life on water , we call that fishing village on the sea. you can also enjoy the fresh seafood, from shrimp, fish, jelly fish to many kinds of seafood that you have never eaten and if you want to cook for yourself , you can do it . Especially , you can try a famous dish of Ha Long jelly fish noodle . I promise that Ha Long bay is a value trip that you should try , the friendly traditional of people in Ha Long , the wonderful lanscape. Imagine you are walking up in the beautiful sunshine amid the rock, islets and caves and seeà the view of Ha Long bay on the top of the mountain will give you a bird-eye view on the bay. I promise that no place in the world has the wonderful view like Ha Long bay. The experience from one to another will lead you to many surprises, the culture, the landscape, cuisine of Ha Long bay . Do not procrastinate , come to Ha Long and enjoy a wonderful gift of nature.
Wednesday, January 22, 2020
The Issues Surrounding the Amazon Rainforest Essay -- Environmental Am
The Issues Surrounding the Amazon Rainforest à à à à à The battle for the Amazon rainforest is a daunting task. Itââ¬â¢s a long going battle between miners, loggers, and developers against the indigenous people who call it home. Itââ¬â¢s a battle like any battle in a war; it affects lives, families, the economy, politics, and the environment amongst other things. The main topic of this debate is the effects of the Amazon deforestation on the people who live in it, this will be the focus of this research paper. In this paper, I will discuss the history, causes, effects and solutions for the Amazon rainforest deforestation. à à à à à The environmental problems of today started a long time ago, before automobiles, electricity, and the Industrial Revolution. From ancient times to present day, humans have changed the world in which they live. As population increase and technology advances, more significant and widespread problems arise. The Amazon rainforest has not been spared from this. The Amazon region has long been seen as a land of great riches. ââ¬Å"Early Europeans and others have long been fascinated by the Amazon, with early visions of a land of gold, the legend of ââ¬ËEl Doradoââ¬â¢Ã¢â¬ (Faminow 32). The European invasion bought with it the increased population and new technologies that had a drastic effect to the Amazonian region, which was once considered safe from exploitation. This problem has continued to the present, with higher consequences. Ehrlich explains, ââ¬Å"today, unprecedented demands on the environment from a rapidly expanding human population and from advan cing technology are causing a continuing and accelerated decline in the quality of the environment and itââ¬â¢s ability to sustain lifeâ⬠(98). As a result, the Amazon rainforest is being destroyed at an alarming rate, affecting all those that live in the region. à à à à à To understand the scope of the changes taking place, Howard Facklam has come up with some staggering statistics, he says, ââ¬Å"it was estimated at one point in the 1980ââ¬â¢s that the Amazon basin was being cleared at the rate of 50 acres a minute; another estimate put the rate at 78,000 square miles per hearâ⬠(53). These are astronomical numbers when you come to think of it, to put it into perspective, thatââ¬â¢s roughly the size of the state of Idaho. Such deforestation has an alarming affect, ââ¬Å"it means the loss of a multiplicity of products: Food, fibers, medicine... ...e papers about it. It doesnââ¬â¢t mean that the problem has gone away, itââ¬â¢s still very much alive. Itââ¬â¢s just not getting the coverage and attention it has before and thatââ¬â¢s where the shame lies. People need to know about this, the more the better. Itââ¬â¢s a valuable resource that mankind cannot afford to lose. Bibliography Ehrlich, Anne et al. Earth. New York: Watts. 2007. Facklam, Howard. Plants: Extinction or Survival?. New Jersey: Enslow. 2000. Faminow, Merle D. Cattle, Deforestation, and Development in the Amazon. New York: CAB International. 2002. Gradwohl, Judith & Russel Greenburg. Saving the Tropical Forests. Washington D.C.. Island Press. 2003. Hecht, Susanna. The Fate of the Forest. London. 2001. Hornaday, Anne. ââ¬Å"Earthââ¬â¢s Threatened Resources.â⬠Congressional Quarterly. 2 Sept. à 2003: 28-29. Linden, Eugene. ââ¬Å"Paradise Lost?â⬠Time. 19 July 2000: 50-51. Smith, Duane A. ââ¬Å"My Trip to the Rain Forest.â⬠Mining America: The Industry and The Environment. 3 Sept. 2001: 66. Stewart, Douglas Ian. After the Trees. Austin: University of Texas Press: 2004. Tropical Deforestation: the human dimension. Ed. Leslie E. Sponsel. New York: Columbia UP. 2006.
Monday, January 13, 2020
Dehumanization in Slavery based on Accounts from Clotel
William Wells Brown warns us that slavery does not only victimize the weak and blacks. In his novel, he points out that ââ¬Å"no one is safeâ⬠from slavery, whether ââ¬Å"white or blackâ⬠(Schweninger 23). In the face of this fact, it seem ironic that the country that is now called the ââ¬Å"land of the freeâ⬠and ââ¬Å"home of the braveâ⬠was once a country where slaves were sold and treated almost with cold blood (Schweninger 23). Indeed, no one is safe, for even a presidentââ¬â¢s daughter has been sold to be a slave. What could be more painful than to be parted from your beloved and your daughter and be sold as a slave, knowing that your daughter would be treated as ill as a servant? This is the Calvary that Clotel had to bear as a slave, though she was, by popular lore, a daughter of the president. And if it were true that she was indeed a daughter of the president (Schweninger 28), would it not be more painful on her part, knowing that she was the daughter of the most powerful man in country, yet she had to be a slave and a concubine? The very thought of this situation dehumanizes Gods masterpiece. There is a rich literature about Brownââ¬â¢s novel, both digital and printed. Most of them bank on the cruelty of slavery. Articlemyriad. com reminds the readers that the novel is fiction, but description of slavery with all its vividness in the accounts of the charactersââ¬â¢ lives is true. It can be well understood how something fictitious can capture the truth behind every word and expression. The writer himself was once a slave, and in fact, the first part of the novel is a biographical account of how he escaped slavery (Analysis and Themes 1). Hence, we see slavery, not in the eyes of someone who has just seen it, but someone who had been a slave, someone who had as firsthand experience of the dehumanizing treatment to slaves. It is not, however, the hard work that Brown resents, but the fact that humans, free or slave are not to be sold (Schweninger 22). At this juncture, it is important to focus more on the historicity of the accounts in the novel. As Articlemyriad. com points out, the novel is fiction, but the accounts are real. No president of the United States would have had a slave daughter, but the experiences of the characters in the novel, from the most ââ¬Å"optimisticâ⬠to the most ââ¬Å"pessimisticâ⬠were not products of imagination (Analysis and Themes 3). As Clotel became a mistress, and was sold, later tried to escape and then commit suicide in despair, Brown was showing a concrete example of what happened to slaves. It was not their fault to be born as mulatto or black or yellow skin, but they faced the discrimination and social prejudice and stereotyping. One example of this stereotyping is stated in the website mentioned. Society does not frown upon the man who sits with his mulatto child upon his knee whilst its mother stands a slave behind his chairâ⬠(Brown 55). We can see from this statement that there is something bout being a mulatto child and a slave mother. A slave, though mother of the masterââ¬â¢s child, remains to be a slave and does not seem to have the right to be wife, and only has the right to be a mistress, a whore. If a white were mother to child of a master, then the master would have to marry her in most cases, of the master would have to face suit, but slaves had no liberty to fight for their rights no matter how disgraced they have been. Though the article points out that the novel is fiction, it gives way to Brownââ¬â¢s claims that the novel is ââ¬Å"no fictionâ⬠(Analysis and Themes 2), for it is ââ¬Å"founded in truthâ⬠(Analysis and Themes 2). The truthfulness of accounts in the novel is what the other two articles by Schweninger and Giulla, although Giullaââ¬â¢s accounts are rather more focused on the language of the blacks. Schweninger puts forth that in as much as the events in the novel could have taken place to slaves; the accounts in the novel were not historically accurate as far as chronology of events is concerned. She mentions several inconsistencies in the chronology of events, one of which is the impossibility of Clotelââ¬â¢s birth in 1798 and ââ¬Å"have her mother witness the 1842 burning when her daughter was only 16â⬠(Schweninger 27). Therefore, according to Schweninger, the point of Brown is not to make a accurate historical account (although he told the readers that the novel is not fiction), but to stress the inhumane treatment to slaves, especially to African Americans and the mulatto. In fact, in the preface of the novel, Brown states ââ¬Å"Were it not for persons in high places owning slavesâ⬠¦ Slavery would have long been abolished. (Schweninger iv). And who were these persons in high places? Brown identifies them as ââ¬Å"professed Christiansâ⬠who give the system (slavery) ââ¬Å"a reputationâ⬠(Schweninger iv). Schweninger suggests that the ââ¬Å"undercutting of the chronology of events stresses that it is not the chronology that is important in the no vel but the universality of the topic and slavery in any year or era would have been the sameâ⬠(Schweninger iv). The people would have suffered just as much and the abusers would have abused the slaves just as much. And as Brown has said, slavery remained not condemned, because the people who had the power to stop it knew its evil but did not want to lose their slaves. They would be hurt in material loses. The battle cry of Brown is not for people to be freed from work. Everyone has to work, but no one deserves to be sold as a slave. Schweninger traces the story of Clotel to another popular lore called Child, where Clotel was originally named Rosalie. She attests that the story of Child was copied word for word except for some insertions by the Brown to express his political views (Schweninger 28). For instance, Scweninger narrates, when Clotel urged the master to move from one place to another, Brown inserted some statements that would highlight the anti-slavery theme of the novel. So, in the original text from Child, the line says ââ¬Å"the slave mistress urged her master ââ¬Ëto remove to France or England (Scweninger 64)â⬠, but in the text of Brown, there is the insertion ââ¬Å"where both her child would be free and where colour was not a crime (Brown 85). Horatio, the master responded to this suggesting her why not reamin her mistress even after he got married. To this, Brown added a text saying, ââ¬Å"True, she was his slave; bones, and sinews had been purchased by his gold, yet she had the heart of a true womanâ⬠(Brown 112). Schweninger also points out that Brown inserted Clotelââ¬â¢s consideration of remaining as a mistress a criminal act (Schweninger 28). Another important matter about the novel is the choice of places to mention. Schweninger confirms the accuracy of the accounts in the place where Currer (Cloteââ¬â¢s mother) was ââ¬â Natchez (Schweninger 29). It was a place, according to Buckingham (from Schweninger 29) where gambling and all sorts of vices were rampant, but most especially, it was a place where people were cruel to slaves. Hence, it was also the site where a runaway slave was burned. Another place mentioned that can be noted for accuracy is Richmond, where Clotelââ¬â¢s daughter was sold. Richmond was, according to Marie Tyler-McGraw (in Schweninger 29) the center of slave trade. It was a powerful place, then, primarily because it was the center of slave brokerage. However, there was some mistake in Brownââ¬â¢s choice for the time when Clotel was caught in Richmond. According to Schweninger, Clotel could not have been caught during the time of the Turner uprising in 1831, because she was mentioning names of presidential candidates of 1839 (Schweninger 30). Yet, Schweninger argues that this ââ¬Å"misplacementâ⬠is of no importance because what was being pointed out here was the she was accused of being a part of the uprising and that was why she was hiding in disguise (Schweninger 30. ). It clear here that Brownââ¬â¢s intention is to show that slaves, too, are humans, capable of upholding morality, and want to uphold morality. They want to do what is right and to be in a place where they can be free, but the people who hold them captives refuse to let them do what they believe is right. Slaves are capable of love and reason, but all that the people who own them see in them is flesh and blood, not human beings with a soul, heart and mind. They were treated as properties and not as members of the society. I believe it pays to go back to Brownââ¬â¢s own words that the institutionalization and rationalization of slavery stated with the people on top, so to stop slavery, then the ââ¬Å"guiltâ⬠should be ââ¬Å"fastenedâ⬠to the people in the ââ¬Å"higher circleâ⬠(Brown iv). When Horatio got married, his wife saw Clotel as a threat so she had her sold. She tried to escape by disguising herself many times. She so got caught by the slave hunters and later committed suicide. This is seen by Articlemyriad. om as the evidence of the idea that the novel does not present optimism or pessimism in whole (Analysis and Themes 1). There were optimistic moments such as those when she was able to escape, yet she still wound up dead by her own will. However, another critique sees the disguises done by Clotel in a different way. Berthold sees every change in costume as a representation of the adversities that Clotel had to face as a female slave (Berthold 19). Guilla argues that male s were connotative for slaves then, so any woman portrayed as a slave would be something new in literature. So, in Bertholdââ¬â¢s explanations, he points out that each time Clotel changes costume, there was something to show about the society and something about her personality and slavery (Berthold 19), even making reference to Brown in the 1880 My Southern Home, ââ¬Å"Extravagance in dress, is a great and growing evil with our peopleâ⬠(Brown 232). For instance, most of Clotelââ¬â¢s disguises were as a white male, just to get out of the situation she was in. It is shown here how people are also judged by their clothing, and so goes with the stereotyping, the gender roles and the power in the gender role. So, if we look into the disguises that Clotel had, she first disguised herself as Mr. Johnson, then as an Italian or Spanish. She actually faced more danger when she disguised herself because she was wearing the shoes of someone whose roles she was not familiar with. When she disguised as a Spanish or Italian, the tension must have been great for she had to speak Italian or Spanish if ever any Spanish or Italian spoke to her. It also, then put her life in danger. Yet, the dangerous attempt got her what she wanted. However, in the end, when she committed suicide, Berthold saw this as ââ¬Å"undisguisingâ⬠herself, one that ascertained freedom for her, for she died as herself, not as anyone else (Berthold 30). Giulla sees the arrangement of the plot as a product of the authorââ¬â¢s effort to expose the life of a community of slaves and need ââ¬Å"to structure the fictional text around the evolution of the individual fate (Guilla 639)â⬠and in so doing, explain the shifts from romance to realism in a exhaustively detailed depiction of slavery and the made-up ââ¬Å"re-unions of long lost relatives and lovers (Guilla 639). If we examine the novel, the members of the family were separated because they were sold to different masters and had different fates. They must have yearned to be with each other as a mother wants to be with her daughter and a daughter with her mother, but the cruelty of slavery kept them from being together, even to the point of their death. This brings us back t o the pessimistic ending that Articlemyriad is talking about. In fact, when one is a slave, what optimism can pone really expect, but a life of hard work and subhuman treatment unless, of course one meets an extraordinary master. But even in the case Clotel, she had romance with Horatio, but the man did not consider his affair with her as something valuable, for if he did, he would have agreed to take her to France or England. We now go back to what I said earlier that slaves were seen as flesh and blood but not as humans with soul and mind. Brownââ¬â¢s style in writing the novel presents and extraordinary mixture of fact and fiction. The story is based on a popular lore that the people then knew, yet he gave it a different touch that made the people understand what was going on. Instead of using male slaves as heroes in the story to enable them to engage in physical confrontations and rebellions, Brown used the female slave to show the beauty and morality behind the mulatto and blacks, that though they were slaves, they had good hearts, and they were good people capable of love and ion need of love, especially in need of love. A show of rebellion could have shown what the society would be if slavery continued, but that was something that was expected to happen (although he made a novel end with a civil war). Brown deemed it more important to show, not the violence that will rise if slavery does not stop, but the impact of slavery to the lives of the people who had been being treated as animals for decades and even centuries by people who profess that they are Christians. To this, it makes a reference to the situation when Clotel disguised herself as Spanish or Italian. These people are known for their devotion in Catholicism. Here, I want to point out that the people who profess that they love God are also the ones who have been showing cruelty to the weak. They were actually hypocrites in a time when religion was strictly followed. We can see from the accounts mentioned by Schweninger that Brown had good accounts in geographical locations, but seems to have had some problems with historical accuracy. However, whether he had problems with chronology of events or he intended them to be such to stress certain points (like in the case of Clotelââ¬â¢s capture during the Turner uprising), his work remains to be a living testament of what happened to the blacks and mulattos in the United States. His work remains to be a loud cry during his time, transcending the boundaries of time to portray the evils of slavery. After all that the blacks and mulattos have experienced, they only deserve to have a part in the land once said to be flowing with milk and honey. The land of opportunity belongs, not only to the whites but also the clacks, and their children. Clotel is a literary treasure, not only to the blacks, but also to the world. It is a legacy, which through it history-based narrative has shown the plight of people in a certain place at a certain point of time. It can be considered a dark age of history, but it is also proof that whenever there is something wrong, the right will also shine.
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